One of the potentially most far reaching and revolutionary ideas in cog-neuro is the suggestion that brain computations are largely intra-neuronal rather than inter-neural. Randy Gallistel has been pushing this idea for the last several years and more and more evidence is pilling up for its feasibility, some of which I have reviewed/mentioned in FoL. Here is another brick in that wall. The authors show how to build "synthetic gene circuits"made up entirely of RNA that form biological "ribocomputing devices." This is a step to "develop biological circuit design strategies that will enable cellular function to be programmed with the same ease hat we program electronic computers." It is obvious to me that should this succeed, it will provide a proof of concept that Gallistel has been on exactly the right track. If correct, it will turn out that brains compute roughly like machines do, and if this happens all the hocus pocus surrounding neural nets and their deep unfathomable properties will, poof, disappear. Recalled as just another wrong turn in the history of science. Personally, I cannot wait.